01PEPTIDE
MOTS-c
Mitochondrial-derived peptide that activates AMPK and supports metabolic flexibility, insulin sensitivity, and exercise capacity.
Mitochondrial HealthEnergyMetabolic
EXPLORE THIS GOAL · EM
Energy + Mitochondria
Cellular energy and oxidative stress. Use this dashboard to move between records, protocols, comparisons, research and tools.
01
Relevant peptides
02PEPTIDE
SS-31 (Elamipretide)
Mitochondria-targeted peptide that stabilizes cardiolipin and improves electron transport chain function.
Mitochondrial HealthEnergyCellular Repair
03PEPTIDE
NAD+
Essential coenzyme for cellular energy production, DNA repair, and sirtuin activity that declines with age.
EnergyMitochondrial HealthCellular Repair
04PEPTIDE
Humanin
A mitochondrial-derived peptide studied in cellular stress, metabolism and age-associated disease models.
Mitochondrial HealthHealthy AgingCellular Repair
05PEPTIDE
Glutathione
Master intracellular antioxidant (often supported by NAC).
Oxidative StressPigmentationCellular Repair
02
Related protocols
03
Popular comparisons
04
Related research
REGULATORYFORZINITY (elamipretide) prescribing informationSS-31 (Elamipretide) · U.S. Food and Drug Administration · 2025CLINICAL TRIALTracing the Metabolic Flux of Orally Administered NAD+NAD+ · ClinicalTrials.gov · 2024HUMANMOTS-c is an exercise-induced mitochondrial-encoded regulator of age-dependent physical decline and muscle homeostasisMOTS-c · Nature Communications · 2021HUMANThe mitochondrial derived peptide humanin is a regulator of lifespan and healthspanHumanin · Aging · 2020HUMANOral Glutathione and Growth in Cystic Fibrosis: A Multicenter, Randomized, Placebo-controlled, Double-blind TrialGlutathione · Journal of Pediatric Gastroenterology and Nutrition · 2020PRECLINICALThe mitochondrial-derived peptide MOTS-c is a regulator of plasma metabolites and enhances insulin sensitivityMOTS-c · Physiological Reports · 2019
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Tools
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Related goals
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