01PEPTIDE
MOTS-c
Mitochondrial-derived peptide that activates AMPK and supports metabolic flexibility, insulin sensitivity, and exercise capacity.
Mitochondrial HealthEnergyMetabolic
EXPLORE THIS GOAL · EM
Energy research
Energy records within Energy + Mitochondria. Structured links are generated from shared research-goal tags.
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Relevant peptides
02PEPTIDE
SS-31 (Elamipretide)
Mitochondria-targeted peptide that stabilizes cardiolipin and improves electron transport chain function.
Mitochondrial HealthEnergyCellular Repair
03PEPTIDE
NAD+
Essential coenzyme for cellular energy production, DNA repair, and sirtuin activity that declines with age.
EnergyMitochondrial HealthCellular Repair
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Related protocols
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Popular comparisons
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Related research
REGULATORYFORZINITY (elamipretide) prescribing informationSS-31 (Elamipretide) · U.S. Food and Drug Administration · 2025CLINICAL TRIALTracing the Metabolic Flux of Orally Administered NAD+NAD+ · ClinicalTrials.gov · 2024HUMANMOTS-c is an exercise-induced mitochondrial-encoded regulator of age-dependent physical decline and muscle homeostasisMOTS-c · Nature Communications · 2021PRECLINICALThe mitochondrial-derived peptide MOTS-c is a regulator of plasma metabolites and enhances insulin sensitivityMOTS-c · Physiological Reports · 2019REVIEWMOTS-c: A novel mitochondrial-derived peptide regulating muscle and fat metabolismMOTS-c · Free Radical Biology and Medicine · 2016PRECLINICALThe mitochondrial-derived peptide MOTS-c promotes metabolic homeostasis and reduces obesity and insulin resistanceMOTS-c · Cell Metabolism · 2015
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