01PEPTIDE
MOTS-c
Mitochondrial-derived peptide that activates AMPK and supports metabolic flexibility, insulin sensitivity, and exercise capacity.
Mitochondrial HealthEnergyMetabolic
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Healthy Aging research
Healthy Aging records within Longevity. Structured links are generated from shared research-goal tags.
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Relevant peptides
02PEPTIDE
SS-31 (Elamipretide)
Mitochondria-targeted peptide that stabilizes cardiolipin and improves electron transport chain function.
Mitochondrial HealthEnergyCellular Repair
03PEPTIDE
NAD+
Essential coenzyme for cellular energy production, DNA repair, and sirtuin activity that declines with age.
EnergyMitochondrial HealthCellular Repair
04PEPTIDE
Epitalon (Epithalon)
Synthetic tetrapeptide (Ala-Glu-Asp-Gly) researched for pineal regulation, telomere support, and longevity signaling.
LongevityHealthy AgingCellular Repair
05PEPTIDE
Humanin
A mitochondrial-derived peptide studied in cellular stress, metabolism and age-associated disease models.
Mitochondrial HealthHealthy AgingCellular Repair
02
Related protocols
03
Popular comparisons
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Related research
REGULATORYFORZINITY (elamipretide) prescribing informationSS-31 (Elamipretide) · U.S. Food and Drug Administration · 2025PRECLINICALEpitalon increases telomere length in human cell lines through telomerase upregulation or ALT activityEpitalon (Epithalon) · Biogerontology · 2025CLINICAL TRIALTracing the Metabolic Flux of Orally Administered NAD+NAD+ · ClinicalTrials.gov · 2024HUMANMOTS-c is an exercise-induced mitochondrial-encoded regulator of age-dependent physical decline and muscle homeostasisMOTS-c · Nature Communications · 2021HUMANThe mitochondrial derived peptide humanin is a regulator of lifespan and healthspanHumanin · Aging · 2020PRECLINICALThe mitochondrial-derived peptide MOTS-c is a regulator of plasma metabolites and enhances insulin sensitivityMOTS-c · Physiological Reports · 2019
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