Potential Benefits
- Accelerated soft-tissue healing (preclinical)
- Gut lining protection
- Potential systemic anti-inflammatory support
RecoveryGutSoft TissueInflammationJoint / Tendon
RESEARCH REFERENCE
BPC-157
Synthetic 15-amino-acid gastric peptide researched for tissue repair, gut protection, and anti-inflammatory effects.
01
Quick Reference
- Dose
- 250–500 mcg/day
- Frequency / schedule
- Daily or split
- Route
- Subcutaneous (near injury or systemic)
- Timing
- Flexible (morning and/or evening)
- Fasting
- Not required — can be taken with or without food
- Cycle
- 4–8 weeks (up to 12 weeks for chronic issues)
- Time off
- 2–4 weeks off
- Common vial strengths
- 5 mg, 10 mg
02
How this works
BPC-157 promotes angiogenesis primarily through activation of the VEGFR2–Akt–eNOS pathway, increases fibroblast migration and survival via FAK/paxillin signaling, modulates nitric oxide, and reduces pro-inflammatory cytokines (IL-6, TNF-α). These overlapping actions accelerate structural repair in animal models of tendon, muscle, and gastrointestinal injury.
03
Benefits + side effects
Side Effects
- Injection-site irritation
- Mild nausea, fatigue, or dizziness (uncommon)
- Theoretical angiogenesis concern with active malignancy
02
Dosing / Protocol
Reference Protocol
| Phase / week | Dose | Frequency | Timing | Notes |
|---|---|---|---|---|
| Standard | 250–350 mcg | 1–2× daily | Flexible | Most common |
| Local | 200–300 mcg | Daily near site | Near injury | For focal injuries |
Timing + Fasting Notes
Flexible timing. Many split AM + PM for more stable levels. Food does not meaningfully affect it.
03
Reconstitution
Approved preparation example
5 mg + 2 mL BAC → 2.5 mg/mL (250 mcg = 10 units)
04
Practical Reference
- Storage
- Lyophilized frozen/refrigerated; reconstituted refrigerated, use within 28 days
- Route / injection context
- Subcutaneous (near injury or systemic)
- Bloodwork / markers
- CRP, CK if injury-related
- Common vial strengths
- 5 mg, 10 mg
- Cycle / time off
- 4–8 weeks (up to 12 weeks for chronic issues) · 2–4 weeks off
- Practical notes
- Rotate sites. Often stacked with TB-500. Research use only.
06
Compare BPC-157 Prices
Current verified products, shown by lowest price per mg first.
FEMETRIC PARTNER
Amino Club
- Product / strength
- BPC-157 · 10 mg × 1
- Current price
- $25.99
- Price / mg
- $2.60
- Availability
- In stock
- Known for
- Public batch certificate library, independent ISO 17025 lab, and multi-assay batch documentation.
- Testing / COA
- Yes
FEMETRIC PARTNER
Apollo Peptide Sciences
- Product / strength
- BPC157 10mg · 10 mg × 1
- Current price
- $59.99
- Price / mg
- $6.00
- Availability
- Listed
- Known for
- Direct variant-level catalog and live stock counts on product pages; free U.S. shipping over $200.
- Testing / COA
- Available / testing data referenced
- FEMETRIC offer
- 10% first order; application/stackability not verified
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References
Gastric pentadecapeptide BPC 157 accelerates healing of transected rat Achilles tendon and in vitro stimulates tendocytes growthJournal of Orthopaedic Research · 2003
PRECLINICAL02Pentadecapeptide BPC 157 (PL 14736) improves ligament healing in the ratJournal of Orthopaedic Research · 2010
PRECLINICAL03The promoting effect of pentadecapeptide BPC 157 on tendon healing involves tendon outgrowth, cell survival, and cell migrationJournal of Applied Physiology · 2011 · DOI 10.1152/japplphysiol.00945.2010
PRECLINICAL04Therapeutic potential of pro-angiogenic BPC157 is associated with VEGFR2 activation and up-regulationJournal of Molecular Medicine · 2017
PRECLINICAL05Gastric pentadecapeptide body protection compound BPC 157 and its role in accelerating musculoskeletal soft tissue healingCell and Tissue Research · 2019 · DOI 10.1007/s00441-019-03016-8
REVIEW06Safety of Intravenous Infusion of BPC157 in HumansJournal of Clinical Medicine · 2025
HUMANTHE SIGNAL · SENT TWICE A MONTH