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Weight ManagementAppetiteFat LossBody Composition

Long-acting amylin analogue · investigational

Cagrilintide

An investigational long-acting amylin analogue studied alone and with semaglutide for weight management. This record separates established identity and source-linked research context from protocol or commercial fields that are not yet supportable.

FEMETRIC RECORD · PUBLICCagrilintide
Weight ManagementAppetiteFat Loss
Status
Clinical Development
Related
4
Sources
1
UPDATED 2026-09-13
01

Protocol references

SOURCE-LINKED

PUBLISHED STUDY

Source-linked research context

No universal administration structure is inferred from the indexed literature. Open the source for the population, intervention and study design.

Route
Subcutaneous
Frequency
See indexed source
Duration
Not indexed
Escalation
Not established
Stage detail pending source extractionStarting and target doses are indexed. Intermediate steps are intentionally not inferred.
PUBLISHED STUDYThe Lancet, 2021Verified 2026-09-13
View primary source
04

How this works

Cagrilintide is an acylated amylin analogue investigated for appetite and weight-related outcomes. Combination studies should not be treated as monotherapy evidence.

Mechanism summaries are stored with field-level source provenance for editorial audit.
07

Related research goals

08

Related peptides

01PEPTIDE

CagriSema

An investigational fixed combination of cagrilintide and semaglutide studied in metabolic and weight-management trials.

Weight ManagementAppetiteGlucose / Insulin
02PEPTIDE

Semaglutide

An approved GLP-1 receptor agonist with formulation- and indication-specific evidence for diabetes, weight management and cardiovascular outcomes.

Weight ManagementAppetiteGlucose / Insulin
03PEPTIDE

Tirzepatide

An approved dual GIP and GLP-1 receptor agonist studied across type 2 diabetes, obesity and cardiometabolic outcomes.

Weight ManagementAppetiteGlucose / Insulin
04PEPTIDE

Retatrutide

An investigational GIP, GLP-1 and glucagon receptor agonist studied for obesity and metabolic outcomes.

Weight ManagementAppetiteGlucose / Insulin
09

Compare Cagrilintide

11

References

01
Once-weekly cagrilintide for weight management in people with overweight and obesityThe Lancet · 2021 · DOI 10.1016/S0140-6736(21)01751-7
CLINICAL TRIAL
Page reviewed: 2026-09-13References updated: 2026-09-13

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