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Skin QualityHairCollagenTissue QualityTissue Repair

Copper-binding tripeptide

GHK-Cu

GHK-Cu is a copper-binding tripeptide with a research history spanning extracellular matrix, wound and cosmetic applications.

FEMETRIC RECORD · PUBLICGHK-Cu
Skin QualityHairCollagen
Status
Preclinical / Research
Related
3
Sources
5
UPDATED 2026-09-09
01

Protocol references

PENDING VERIFICATION

PLACEHOLDER / UNVERIFIED

Subcutaneous planning sample

Planning fields are pending route-specific source and formulation review.

Route
Subcutaneous research
Frequency
5× weekly
Duration
8 weeks
Escalation
Not established
STAGEWEEKSSTUDY DOSE
11–521 mg · 5×/wk
PLACEHOLDER / UNVERIFIEDFemetric planning field under editorial reviewVerified 2026-09-09
03

Supply / calculator inputs

01 · STUDY SOURCESubcutaneous planning sampleFemetric planning field under editorial reviewPENDING VERIFICATION
02 · PREPARATION INPUT50 mg planning vialFemetric planning inputPENDING VERIFICATION
03 · DERIVED ESTIMATE1 vial40 mg across 8 weeks
40 mgPeptide total
1Research vials
3 mLBAC water
40Administrations

Study dose data and preparation inputs are separate records. Changing vial or liquid settings does not change the published study arm.

04

How this works

GHK binds copper and has been studied in relation to fibroblast activity, extracellular-matrix signaling and tissue remodeling. Much of the mechanistic evidence is laboratory or preclinical, and findings vary by formulation and route.

Mechanism summaries are stored with field-level source provenance for editorial audit.
07

Related research goals

08

Related peptides

01PEPTIDE

KLOW

A vendor-defined blend name commonly combining repair, inflammatory and cosmetic research peptides.

Skin QualityCollagenInflammation
02PEPTIDE

Glutathione

A naturally produced antioxidant researched in oxidative stress, redox balance and pigmentation contexts.

Oxidative StressPigmentationCellular Repair
03PEPTIDE

BPC-157

A gastric-derived research peptide studied primarily in preclinical tissue-repair and gastrointestinal models.

RecoveryGutSoft Tissue
09

Compare GHK-Cu

COMMERCIAL DISPLAY · PENDING REVIEW

Vendor architecture is retained, but commerce is not displayed until product and policy review are complete.

11

References

01
Stimulation of collagen synthesis in fibroblast cultures by the tripeptide-copper complex glycyl-L-histidyl-L-lysine-Cu2+FEBS Letters · 1988
PRECLINICAL02
The human tri-peptide GHK and tissue remodelingJournal of Biomaterials Science · 2008
REVIEW03
In vitro observations on the influence of copper peptide aids for the LED photoirradiation of fibroblast collagen synthesisPhotomedicine and Laser Surgery · 2007 · DOI 10.1089/pho.2007.2062
PRECLINICAL04
Effects of topical copper tripeptide complex on CO2 laser-resurfaced skinArchives of Facial Plastic Surgery · 2006
HUMAN05
Regenerative and Protective Actions of the GHK-Cu Peptide in the Light of the New Gene DataInternational Journal of Molecular Sciences · 2018
REVIEW
Page reviewed: 2026-09-09References updated: 2026-09-09

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