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Mitochondrial HealthHealthy AgingCellular RepairOxidative Stress

Mitochondrial-derived peptide

Humanin

A mitochondrial-derived peptide studied in cellular stress, metabolism and age-associated disease models. This record separates established identity and source-linked research context from protocol or commercial fields that are not yet supportable.

FEMETRIC RECORD · PUBLICHumanin
Mitochondrial HealthHealthy AgingCellular Repair
Status
Preclinical / Research
Related
4
Sources
1
UPDATED 2026-09-13
01

Protocol references

SOURCE-LINKED

LITERATURE-DERIVED REFERENCE

Source-linked research context

No universal administration structure is inferred from the indexed literature. Open the source for the population, intervention and study design.

Route
Source dependent
Frequency
See indexed source
Duration
Not indexed
Escalation
Not established
Stage detail pending source extractionStarting and target doses are indexed. Intermediate steps are intentionally not inferred.
LITERATURE-DERIVED REFERENCEAging, 2020Verified 2026-09-13
View primary source
04

How this works

Humanin is encoded within mitochondrial ribosomal RNA and has been investigated as a stress-responsive signaling peptide. Most intervention evidence remains preclinical.

Mechanism summaries are stored with field-level source provenance for editorial audit.
07

Related research goals

08

Related peptides

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Mitochondrial HealthEnergyMetabolic
02PEPTIDE

SS-31 / Elamipretide

A mitochondria-targeted peptide with clinical research across mitochondrial disorders and a U.S. accelerated approval for Barth syndrome.

Mitochondrial HealthEnergyCellular Repair
03PEPTIDE

NAD+

An endogenous coenzyme central to redox chemistry and cellular energy, distinct from its oral precursor compounds.

EnergyMitochondrial HealthCellular Repair
04PEPTIDE

Epitalon / Epithalon

A synthetic tetrapeptide studied mainly in cellular and preclinical aging models, with limited independently replicated human evidence.

LongevityHealthy AgingCellular Repair
09

Compare Humanin

11

References

01
The mitochondrial derived peptide humanin is a regulator of lifespan and healthspanAging · 2020
HUMAN
Page reviewed: 2026-09-13References updated: 2026-09-13

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