An endogenous neuropeptide central to GnRH signaling, studied in reproductive endocrinology and psychosexual research. This record separates established identity and source-linked research context from protocol or commercial fields that are not yet supportable.
FEMETRIC RECORD · PUBLICKisspeptin
Reproductive SignalingNeuroendocrineLibido
Status
Investigational
Related
2
Sources
1
UPDATED 2026-09-13
01
Protocol references
SOURCE-LINKED
PUBLISHED STUDY
Source-linked research context
No universal administration structure is inferred from the indexed literature. Open the source for the population, intervention and study design.
Route
Intravenous research
Frequency
See indexed source
Duration
Not indexed
Escalation
Not established
Stage detail pending source extractionStarting and target doses are indexed. Intermediate steps are intentionally not inferred.
PUBLISHED STUDYJAMA Network Open, 2022Verified 2026-09-13
Kisspeptin activates KISS1R and stimulates hypothalamic GnRH pathways. Responses vary with sex and menstrual-cycle context, making women-specific metadata especially relevant.
Mechanism summaries are stored with field-level source provenance for editorial audit.
05
Women in the research
FEMALE REPRESENTATION100.0%40 of 40 participants
DOSE STRUCTURENot reportedNo separate “women’s dose” was defined.
SEX-SPECIFIC FINDINGSReported as an exploratory subgroupThirty-two women completed both visits. The trial reported neuroimaging, psychometric and hormonal outcomes in women with HSDD.
Premenopausal women; menstrual-cycle and hormonal-contraception context was controlled in the study design.