Search Femetric

Search peptides, goals, protocols and references

LibidoSexual WellnessNeuroendocrine

Melanocortin receptor agonist

PT-141 / Bremelanotide

A melanocortin receptor agonist approved in the U.S. for acquired, generalized HSDD in premenopausal women under defined label conditions. This record separates established identity and source-linked research context from protocol or commercial fields that are not yet supportable.

FEMETRIC RECORD · PUBLICPT-141 / Bremelanotide
LibidoSexual WellnessNeuroendocrine
Status
Approved
Related
2
Sources
1
UPDATED 2026-09-13
01

Protocol references

SOURCE-LINKED

PUBLISHED STUDY

Source-linked research context

No universal administration structure is inferred from the indexed literature. Open the source for the population, intervention and study design.

Route
Subcutaneous
Frequency
See indexed source
Duration
Not indexed
Escalation
Not established
Stage detail pending source extractionStarting and target doses are indexed. Intermediate steps are intentionally not inferred.
PUBLISHED STUDYObstetrics & Gynecology, 2019Verified 2026-09-13
View primary source
04

How this works

Bremelanotide acts through melanocortin receptors in the central nervous system. Its evidence and approval are explicitly women-specific and indication-specific.

Mechanism summaries are stored with field-level source provenance for editorial audit.
05

Women in the research

FEMALE REPRESENTATION100.0%1267 of 1267 participants
DOSE STRUCTURENot reportedNo separate “women’s dose” was defined.
SEX-SPECIFIC FINDINGSReported as an exploratory subgroupThe two phase 3 trials enrolled premenopausal women and reported female sexual desire, related distress and adverse events; 1,247 were included in the safety population.

Premenopausal women with acquired, generalized HSDD.

View source
07

Related research goals

08

Related peptides

01PEPTIDE

Kisspeptin

An endogenous neuropeptide central to GnRH signaling, studied in reproductive endocrinology and psychosexual research.

Reproductive SignalingNeuroendocrineLibido
02PEPTIDE

Oxytocin

A peptide hormone with established obstetric uses and research spanning lactation, social processing and sexual function.

Sexual WellnessReproductive SignalingNeuroendocrine
09

Compare PT-141 / Bremelanotide

11

References

01
Bremelanotide for the Treatment of Hypoactive Sexual Desire Disorder: Two Randomized Phase 3 TrialsObstetrics & Gynecology · 2019
CLINICAL TRIAL
Page reviewed: 2026-09-13References updated: 2026-09-13

THE SIGNAL

The research worth knowing.

Peptides, emerging performance research and new Femetric tools.
NEXT RESEARCH ACTION
Was this useful?