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Weight ManagementAppetiteFat LossGlucose / InsulinBody Composition

GLP-1 / glucagon dual agonist · investigational

Survodutide

An investigational GLP-1 and glucagon receptor dual agonist in clinical development for obesity and metabolic liver disease. This record separates established identity and source-linked research context from protocol or commercial fields that are not yet supportable.

FEMETRIC RECORD · PUBLICSurvodutide
Weight ManagementAppetiteFat Loss
Status
Clinical Development
Related
4
Sources
1
UPDATED 2026-09-13
01

Protocol references

SOURCE-LINKED

PUBLISHED STUDY

Source-linked research context

No universal administration structure is inferred from the indexed literature. Open the source for the population, intervention and study design.

Route
Subcutaneous
Frequency
See indexed source
Duration
Not indexed
Escalation
Not established
Stage detail pending source extractionStarting and target doses are indexed. Intermediate steps are intentionally not inferred.
PUBLISHED STUDYThe Lancet Diabetes & Endocrinology, 2024Verified 2026-09-13
View primary source
04

How this works

Survodutide activates GLP-1 and glucagon receptors. Human phase 2 studies used source-defined escalation and maintenance periods that should not be simplified into a universal schedule.

Mechanism summaries are stored with field-level source provenance for editorial audit.
07

Related research goals

08

Related peptides

01PEPTIDE

Retatrutide

An investigational GIP, GLP-1 and glucagon receptor agonist studied for obesity and metabolic outcomes.

Weight ManagementAppetiteGlucose / Insulin
02PEPTIDE

Mazdutide

A GLP-1 and glucagon receptor dual agonist studied in obesity and type 2 diabetes, with development and regulatory status varying by region.

Weight ManagementGlucose / InsulinFat Loss
03PEPTIDE

Pemvidutide

An investigational GLP-1 and glucagon receptor dual agonist studied for obesity and metabolic liver disease.

Weight ManagementFat LossBody Composition
04PEPTIDE

Tirzepatide

An approved dual GIP and GLP-1 receptor agonist studied across type 2 diabetes, obesity and cardiometabolic outcomes.

Weight ManagementAppetiteGlucose / Insulin
09

Compare Survodutide

11

References

01
Glucagon and GLP-1 receptor dual agonist survodutide for obesityThe Lancet Diabetes & Endocrinology · 2024 · DOI 10.1016/S2213-8587(23)00356-X
CLINICAL TRIAL
Page reviewed: 2026-09-13References updated: 2026-09-13

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