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Body CompositionFat LossNeuroendocrine

Growth hormone-releasing factor analogue

Tesamorelin

A GHRF analogue approved for reduction of excess abdominal fat in adults with HIV and lipodystrophy, with additional research contexts. This record separates established identity and source-linked research context from protocol or commercial fields that are not yet supportable.

FEMETRIC RECORD · PUBLICTesamorelin
Body CompositionFat LossNeuroendocrine
Status
Approved
Related
3
Sources
1
UPDATED 2026-09-13
01

Protocol references

SOURCE-LINKED

PUBLISHED STUDY

Source-linked research context

No universal administration structure is inferred from the indexed literature. Open the source for the population, intervention and study design.

Route
Subcutaneous
Frequency
See indexed source
Duration
Not indexed
Escalation
Not established
Stage detail pending source extractionStarting and target doses are indexed. Intermediate steps are intentionally not inferred.
PUBLISHED STUDYJAMA, 2014Verified 2026-09-13
View primary source
04

How this works

Tesamorelin stimulates pituitary growth hormone release and downstream IGF-1. Findings in HIV-associated lipodystrophy do not automatically generalize to other body-composition contexts.

Mechanism summaries are stored with field-level source provenance for editorial audit.
07

Related research goals

08

Related peptides

01PEPTIDE

Sermorelin

A GHRH(1-29) analogue formerly approved for pediatric diagnostic and treatment contexts and later discontinued commercially.

NeuroendocrineBody CompositionRecovery
02PEPTIDE

CJC-1295

A long-acting growth hormone-releasing hormone analogue studied in healthy adults for GH and IGF-1 pharmacodynamics.

NeuroendocrineBody CompositionRecovery
03PEPTIDE

Ipamorelin

A selective ghrelin-receptor agonist studied as a growth hormone secretagogue, with limited modern human clinical evidence.

NeuroendocrineBody CompositionRecovery
09

Compare Tesamorelin

11

References

01
Effect of Tesamorelin on Visceral Fat and Liver Fat in HIV-Infected Patients With Abdominal Fat AccumulationJAMA · 2014
CLINICAL TRIAL
Page reviewed: 2026-09-13References updated: 2026-09-13

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